Redaccion
Researchers from the Hospital Clínico San Carlos de Madrid have successfully reversed androgenic alopecia – or common baldness – in mice using cellular therapy, the first discovery of its kind to be published worldwide, opening up new possibilities in regenerative hair treatment.
This research, in collaboration with the Biomedical Research Foundation of the Hospital Clínico San Carlos, was conducted on an experimental model of mice induced with alopecia by administering the hormone responsible for hair loss. The study evaluated the efficacy of stem cells derived from adipose tissue in different doses and combinations with adenosine triphosphate, as detailed by the Madri+d Knowledge Foundation.
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According to the results of the study conducted by researchers at this public hospital in Madrid, 100% of male mice that received low doses of stem cells and adenosine triphosphate treatment regrew hair, with 50% of them regrowing completely and the other 50% intensely; while in female mice, 90% regrew hair with moderate doses of stem cells and the energizing molecule. Of these, 50% achieved complete regrowth and 40% intense regrowth.
The combination of stem cells derived from adipose tissue and adenosine triphosphate «stimulates hair regeneration by combining the regenerative capacity of the former with the energy provided by the latter. This synergy promotes hair follicle recovery, encouraging hair growth,» explains Eduardo López Bran, Head of the Dermatology Service at the Hospital Clínico San Carlos.
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Currently, there are various treatments for hair loss including pharmacological therapies, laser hair therapy, platelet-rich plasma, and follicular unit transplantation, although they all have certain limitations.
Although the results of this research are promising, the authors point out that additional clinical trials will be needed to confirm its efficacy and safety in humans.
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This study opens the door to the possibility of treating alopecia through a non-invasive process.
The research highlights the potential of personalized treatments, leveraging the regenerative properties of stem cells derived from adipose tissue and the ability of adenosine triphosphate to enhance cellular metabolism.
